1013910-57-0Relevant articles and documents
Enantioselective addition of nitromethane to α-keto esters catalyzed by copper(II)-iminopyridine complexes
Blay, Gonzalo,Hernandez-Olmos, Victor,Pedro, Jose R.
experimental part, p. 468 - 476 (2008/10/09)
The copper complex of a chiral iminopyridine easily prepared from (R)-(-)-fenchone and picolylamine catalyzes the enantioselective Henry (nitroaldol) reaction between nitromethane and α-keto esters. Good yields and modest to good enantioselectivities are obtained for a wide range of α-keto esters, bearing aromatic, alkyl or alkenyl groups attached to the ketone carbonyl group. The Royal Society of Chemistry 2008.