1013933-93-1

Basic information

• Product Name: 3,4-dihydro-5,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)coumarin
• Synonyms: 3,4-dihydro-5,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)coumarin
• CAS NO: 1013933-93-1
• Molecular Weight: 374.39
• Mol File: 1013933-93-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-dihydro-5,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)coumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-5,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)coumarin(1013933-93-1)
• EPA Substance Registry System: 3,4-dihydro-5,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)coumarin(1013933-93-1)

Safety Data

• Hazardous Substances Data: 1013933-93-1(Hazardous Substances Data)

Upstream product

• 500-99-2 3,5-dimethoxyphenol 
• 7560-49-8 3,4,5-trimethoxycinnamic acid methyl ester 

Downstream Products

• 1064065-75-3 3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(1H-pyrrol-1-yl)-3-(3,4,5-trimethoxyphenyl)propan-1-one 

Relevant articles and documents

Design and synthesis of C-ring lactone- and lactam-based podophyllotoxin analogues as anticancer agents

A series of novel podophyllotoxin (PDT) analogues was synthesized in which the lactone moiety was shifted to C ring. Some of the derivatives were also synthesized with modified A ring. Analogues 23 and 25 exhibited potent in vitro cytotoxicity against colon cancer (CaCO2) cell line. p-Demethylated E-ring analogues exhibited better potency than the corresponding methylated analogues. These analogues showed toxicity comparable to PDT against human erythrocytes albeit at much higher concentrations (100 μg/ml) than their cytotoxicity values.