101596-87-6

Basic information

• Product Name: 2-phenyl-7-methoxytetralone
• Synonyms: 2-phenyl-7-methoxytetralone
• CAS NO: 101596-87-6
• Molecular Weight: 252.313
• Mol File: 101596-87-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenyl-7-methoxytetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-7-methoxytetralone(101596-87-6)
• EPA Substance Registry System: 2-phenyl-7-methoxytetralone(101596-87-6)

Safety Data

• Hazardous Substances Data: 101596-87-6(Hazardous Substances Data)

Upstream product

• 6836-19-7 7-Methoxy-1-tetralone 
• 108-86-1 bromobenzene 
• 1730-48-9 6-methoxy-1,2,3,4-tetrahydronaphthalene 
• 108-90-7 chlorobenzene 
• 20176-04-9 1-Acetoxy-7-methoxy-3.4-dihydro-naphthalin 

Downstream Products

• 13623-25-1 6-methoxy-2,3-dihydro-1H-inden-1-one 
• 1159602-73-9 (7-methoxy-2-phenyl-3,4-dihydro-2H-naphthalen-1-ylidene)acetonitrile 

Relevant articles and documents

Blue Light Promoted Difluoroalkylation of Aryl Ketones: Synthesis of Quaternary Alkyl Difluorides and Tetrasubstituted Monofluoroalkenes

A facile and cost-effective method for the preparation of fluoroalkylated compounds has been described by the direct photoexcitation of halofluoroalkanes with blue light absorptivity, enabling the difluoroalkylation of aryl ketones. The methodology has provided an efficient, mild, and catalyst-free synthetic method for quaternary difluoroalkylated arenes and tetrasubstituted monofluoroalkenes.

Inhibitors of acyl CoA:cholesterol acyltransferase

Conformational restriction of previously disclosed acyclic diphenylethyl)diphenylacetamides led to the discovery of several potent inhibitors of acyl CoA:cholesterol acyltransferase (ACAT). cis-[2-(4- Hydroxyphenyl)-1-indanyl]diphenylacetamide (4a) was the most potent ACAT inhibitor identified (IC50 = 0.04 μM in an in vitro rat hepatic microsomal ACAT assay, ED50 = 0.72 mg/kg/day in cholesterol-fed hamsters).