10162-58-0 Usage
Description
7-methylguanosine-5'-monophosphate is a chemical compound that consists of a guanosine molecule with a methyl group attached to the seventh carbon atom. It is a monophosphate ester, which means it has one phosphate group attached to the 5' carbon of the ribose ring. 7-methylguanosine-5'-monophosphate plays a significant role in biological processes such as RNA metabolism and protein synthesis.
Uses
Used in Biochemistry Research:
7-methylguanosine-5'-monophosphate is used as a research tool for studying the structure and function of transfer RNA (tRNA). Its presence in tRNA contributes to the stabilization of the tRNA molecule and aids in the proper binding of amino acids during protein synthesis.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 7-methylguanosine-5'-monophosphate is being investigated for its potential role in cancer therapy. It may be involved in the regulation of cell growth and proliferation, making it a candidate for the development of new therapeutic agents targeting cancer cells.
Used in Diagnostic Applications:
7-methylguanosine-5'-monophosphate can be utilized in diagnostic applications to assess the presence or activity of certain biological processes related to RNA metabolism and protein synthesis. This can help in understanding the underlying mechanisms of diseases and in the development of diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 10162-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10162-58:
(7*1)+(6*0)+(5*1)+(4*6)+(3*2)+(2*5)+(1*8)=60
60 % 10 = 0
So 10162-58-0 is a valid CAS Registry Number.
10162-58-0Relevant articles and documents
Regio-selective synthesis of polyazacyclophanes incorporating a pendant group as potential cleaving agents of mRNA 5′-cap structure
Zhang, Zhibo,Mikkola, Satu,Lonnberg, Harri
, p. 11716 - 11723 (2008/03/14)
A terpyridine or an imidazole unit has been tethered to an N-protected polyazacyclophane to give the appropriate N-monofunctionalized polyazacyclophane. After mild deprotection, four polyazacyclophanes incorporating a pendant group were obtained in satisf
The Cu2+-promoted cleavage of mRNA 5'-cap analogs: A kinetic study with p1(7-methylguanosin-5'-yl) p3-(nucleosid-5'-yl) triphospates and p1- (7-methylguanosin-5'-yl) p4-(guanosin-5'-yl) tetraphosphate
Wieczorek, Zbigniew,Darzynkiewicz, Edward,Kuusela, Satu,Loennberg, Harri
, p. 11 - 21 (2007/10/03)
A kinetic study on the cleavage of a number of mRNA 5'-cap analogs, m7GpppN and m7GppppG, with Cu2+ aquo ion has been performed. Time- dependent product distributions at various pH and metal ion concentrations have been determined by capillary zone electrophoresis, and these data have been used to calculate the rate constants for various parallel reactions of the breakdown of the cap analogs.