1016228-23-1

Basic information

• Product Name: C₂₆H₂₉ClN₄O
• CAS NO: 1016228-23-1
• Molecular Weight: 448.995
• Mol File: 1016228-23-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₉ClN₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₉ClN₄O(1016228-23-1)
• EPA Substance Registry System: C₂₆H₂₉ClN₄O(1016228-23-1)

Safety Data

• Hazardous Substances Data: 1016228-23-1(Hazardous Substances Data)

Upstream product

• 38212-33-8 4-(4-chlorophenyl) piperazine 
• 5878-43-3 9,10-dihydrolysergic acid 

Relevant articles and documents

Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst1 receptor

Non-peptidic compounds containing the octahydro-indolo[4,3-fg]quinoline (ergoline) structural element have been optimized into derivatives with high affinity (pKd r sst1 > 9) and selectivity (>1000-fold for h sst1 over h sst2-h sst5) for the somatostatin sst1 receptor. In functional assays, these ergolines act as antagonists at human recombinant sst1 receptors. Pharmacokinetic studies in rodents reveal good oral bioavailability and brain penetration for some of these compounds.