101623-22-7

Basic information

• Product Name: L-Phenylalanine, N-[N-(phenylacetyl)-L-a-aspartyl]-, 1-methyl ester
• CAS NO: 101623-22-7
• Molecular Formula: C22H24N2O6
• Molecular Weight: 412.442
• Mol File: 101623-22-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[N-(phenylacetyl)-L-a-aspartyl]-, 1-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[N-(phenylacetyl)-L-a-aspartyl]-, 1-methyl ester(101623-22-7)
• EPA Substance Registry System: L-Phenylalanine, N-[N-(phenylacetyl)-L-a-aspartyl]-, 1-methyl ester(101623-22-7)

Safety Data

• Hazardous Substances Data: 101623-22-7(Hazardous Substances Data)

Upstream product

• 115929-98-1 Ac(Ph)-Asp-Phe-OMe*H-Phe-OMe 

Downstream Products

• 103-82-2 phenylacetic acid 
• 22839-47-0 L-Asp-L-Phe-OMe 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 2752-32-1 N-phenylacetyl aspartic acid 

Relevant articles and documents

Enzymic synthesis design and enzymic synthesis of aspartame

An enzymic synthesis of aspartame (H-Asp-Phe-OMe) has been designed and realized based on the structure-activity study of thermolysin and penicillin amidase hydrolysis of its p-substituted phenylacetyl derivatives. These compounds meet the structural and energetic requirements of two enzymic binding sites. The peptide sweetener has been prepared by thermolysin - catalyzed condensation of the p-substituted phenylacetyl-Asp-OH and H-Phe-OMe follwed by penicillin amidase - catalyzed deprotection of the resulted aspartame precursors.