101625-10-9Relevant articles and documents
Toward Efficient Zn(II)-Based Artificial Nucleases
Boseggia, Elisa,Gatos, Maddalena,Lucatello, Lorena,Mancin, Fabrizio,Moro, Stefano,Palumbo, Manlio,Sissi, Claudia,Tecilla, Paolo,Tonellato, Umberto,Zagotto, Giuseppe
, p. 4543 - 4549 (2007/10/03)
A series of cis-cis-triaminocyclohexane Zn(II) complex-anthraquinone intercalator conjugates, designed in such a way to allow their easy synthesis and modification, have been investigated as hydrolytic cleaving agents for plasmid DNA. The ligand structure
Selective synthesis and kinetic measurement of 1:1 and 2:2 cyclic compounds containing 1,4,7,10-tetraazacyclododecane and azobenzene units
Wei,Tomohiro,Kodaka,Okuno
, p. 8979 - 8987 (2007/10/03)
1:1 cyclic compounds 8a-c (51-55%) and 2:2 cyclic compounds 9a-c (20-49%) containing 1,4,7,-10-tetraazacyclododecane (cyclen) and azobenzene units were selectively synthesized under UV irradiation (330 nm ?, ΔH?, and ΔS?) of 8a-c and 9a-c were studied in nonpolar media (benzene) and polar media (methanol). The cis to trans isomerization rates in the dark for these cyclic compounds increase with ring size or structural flexibility (8a ? dominates ΔG? in cyclic compounds.
SUBSTITUTED PROLINE COMPOUNDS, COMPOSITION AND METHOD OF USE
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, (2008/06/13)
Compounds of the formula STR1 are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity.