1017-10-3

Basic information

• Product Name: 5-Butyl-3-phenylisoxazole
• Synonyms: 5-Butyl-3-phenylisoxazole
• CAS NO: 1017-10-3
• Molecular Formula: C₁₃H₁₅NO
• Molecular Weight: 201.26
• Mol File: 1017-10-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Butyl-3-phenylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Butyl-3-phenylisoxazole(1017-10-3)
• EPA Substance Registry System: 5-Butyl-3-phenylisoxazole(1017-10-3)

Safety Data

• Hazardous Substances Data: 1017-10-3(Hazardous Substances Data)

Upstream product

• 693-02-7 hex-1-yne 
• 932-90-1 Benzaldoxime 
• 100-52-7 benzaldehyde 
• 18998-78-2 1-phenyl-hept-2-yn-1-one 
• 1313396-12-1 (1Z)-1-phenyl-2-heptyn-1-one O-(phenylmethyl)oxime 
• 73922-80-2 1-phenylhept-2-yn-1-ol 
• 1257652-64-4 N-hydroxy-N-(1-phenylhept-2-ynyl)benzenesulfonamide 
• 932-90-1 syn-benzaldehyde oxime 
• 873-67-6 benzonitrile oxide 
• 1191-12-4 1-hexynyltrimethylstannane 

Relevant articles and documents

Green preparation method of isoxazole compound participating in water-soluble vitamin E

The invention provides a green synthesis method of an isoxazole compound represented by the formula (III), wherein the aldehyde oxime compound represented by the formula (I) is a substrate and is in an aqueous solution of a surfactant with a mass concentration 1 wt % - 5 wt % in N - chlorosuccinimide. The alkyne compound represented by the formula (II) is reacted 6 - 16h at room temperature under the common action of the basic substance, and the resulting reaction solution is post-treated to obtain the isoxazole compound represented by the formula (III). Water serves as a reaction solvent, the use amount of the organic solvent is reduced, and zero emission of the solvent is realized.

Rhodium(II)-Catalyzed Formal [3 + 2] Cycloaddition of N-Sulfonyl-1,2,3-triazoles with Isoxazoles: Entry to Polysubstituted 3-Aminopyrroles

A novel rhodium(II)-catalyzed formal [3 + 2] cycloaddition of N-sulfonyl-1,2,3-triazoles with isoxazoles has been achieved that provides an efficient method for the synthesis of polysubstituted 3-aminopyrrole derivatives. An operationally simple one-pot synthesis of the titled compounds from terminal alkynes, tosyl azide, and isoxazoles was also developed. The presented reaction affords an illustrative example of employing 1,2,3-triazoles as the [2C]-component in relevant cycloaddition reactions.

Silver-catalyzed synthesis of disubstituted isoxazoles by cyclization of alkynyl oxime ethers

A facile and practical synthesis of 3,5-disubstituted isoxazoles via a silver-catalyzed cyclization and subsequent protonation of alkynyl oxime ethers has been developed. The methodology was successfully applied to the synthesis of a biologically active i