1017587-22-2Relevant articles and documents
Palladium(II)-catalyzed cyclization of urethanes and its application to a total synthesis of 1-deoxynojirimycin
Yokoyama, Hajime,Kobayashi, Hisatake,Miyazawa, Masahiro,Yamaguchi, Seiji,Hirai, Yoshiro
, p. 283 - 292 (2008/09/17)
We have employed a palladium(II)-catalyzed cyclization of allylic alcohol as a key reaction to achieve a total synthesis of the azasugar 1-deoxynojirimycin from o-mannitol. This reaction should be useful for the stereoselective construction of natural poly-substituted piperidine derivatives.