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101799-75-1

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101799-75-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 101799-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,7,9 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 101799-75:
(8*1)+(7*0)+(6*1)+(5*7)+(4*9)+(3*9)+(2*7)+(1*5)=131
131 % 10 = 1
So 101799-75-1 is a valid CAS Registry Number.

101799-75-1Relevant articles and documents

Chlorination at the 8-position of a functionalized quinolone and the synthesis of quinolone antibiotic ABT-492

Barnes, David M.,Christesen, Alan C.,Engstrom, Kenneth M.,Haight, Anthony R.,Hsu, Margaret C.,Lee, Elaine C.,Peterson, Matthew J.,Plata, Daniel J.,Raje, Prasad S.,Stoner, Eric J.,Tedrow, Jason S.,Wagaw, Seble

, p. 803 - 807 (2006)

The total synthesis of quinolone antibiotic ABT-492 has been achieved in 67% yield over nine steps from 2,4,5-trifluorobenzoic acid. The highlights of this synthesis include a novel chemoselective chlorination at the 8-position of a highly elaborated quinolone core. In addition, a Lewis acid promoted cyclization reaction to form the quinolone heterocycle was developed which was incorporated into a one-pot, three-step cyclization/coupling/protection sequence that proceeds in 93% yield.

Probing structural requirements for human topoisomerase I inhibition by a novel N1-Biphenyl fluoroquinolone

Delgado, Justine L.,Lentz, Sarah R.C.,Kulkarni, Chaitanya A.,Chheda, Pratik R.,Held, Hailey A.,Hiasa, Hiroshi,Kerns, Robert J.

, p. 109 - 130 (2019)

Fluoroquinolones substituted with N-1 biphenyl and napthyl groups were discovered to act as catalytically inhibitors of human topoisomerases I and II, and to possess anti-proliferative activity in vivo. Structural requirements for these novel quinolones t

Syntheses of new pyridonecarboxylic acid derivatives containing 1- or 2- naphthyl substituents at N-1 and their anti-HIV-RT activities

Oh,Cho

, p. 17 - 23 (1998)

A series of new pyridonecarboxylic acid derivatives containing 1- or 2- naphthyl substituents at N-1 were synthesized at their in vitro anti-HIV-RT activities were evaluated. Several compounds in this series showed better activity than Atevirdine.

A kind of improved [...] preparation method (by machine translation)

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Paragraph 0036, (2018/03/24)

The invention belongs to the field of medical synthesis, in particular to a kind of improved [...] preparation method. The technology of this invention can avoid a 4 - benzopyran [...] formation of impurities, and follow-up substituted, cyclized, butt joi

QUINOLONE-BASED COMPOUNDS WITH ANTICANCER ACTIVITY

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Paragraph 0087, (2018/06/30)

Embodiments are directed to compounds of the formulae (I), (Ia), (Ib), (II), (IIa) (III), (IV), (V), and (VI); methods for treating cancer with one or more compounds of the formulae (I), (Ia), (Ib), (II), (IIa); (III), (IV), (V), and (VI); and methods for

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