1018467-70-3

Basic information

• Product Name: N-(4-methyl-3-(5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide
• Synonyms: N-(4-methyl-3-(5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide
• CAS NO: 1018467-70-3
• Molecular Weight: 498.532
• Mol File: 1018467-70-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-methyl-3-(5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methyl-3-(5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide(1018467-70-3)
• EPA Substance Registry System: N-(4-methyl-3-(5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide(1018467-70-3)

Safety Data

• Hazardous Substances Data: 1018467-70-3(Hazardous Substances Data)

Upstream product

• 99469-77-9 (6-methylsulfanylpyrimidin-4-yl)hydrazine 
• 89283-48-7 4-chloro-6-methylsulfanylpyrimidine 
• 876322-59-7 N-(3-bromo-4-methylphenyl)-3-(trifluoromethyl)benzamide 
• 1018473-15-8 5-methyl-2-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamine 

Downstream Products

• 1018473-16-9 N-(3-(2-(6-methanesulfinylpyrimidin-4-yl)-5-methyl-2H-pyrazol-3-ylamino)-4-methylphenyl)-3-trifluoromethylbenzamide 
• 1018467-34-9 N-(4-methyl-3-(5-methyl-4-(6-(2-morpholin-4-ylethylamino)pyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.