101890-98-6Relevant articles and documents
Substituted 4,6-Diaminoquinolines as Inhibitors of C5a Receptor Binding
Lanza, Thomas J.,Durette, Philippe L.,Rollins, Thomas,Siciliano, Salvatore,Cianciarulo, Dana N.,et al.
, p. 252 - 258 (2007/10/02)
The anaphylatoxin C5a is implicated in a number of inflammatory diseases.It is a highly cationic protein with 13 of 74 amino acids being either arginine or lysine.A search focusing on positively charged molecules, particularly amine-containing functionali