1020073-90-8

Basic information

• Product Name: 3,4-dibenzyloxy-N-[3-(4-benzyloxy)-1-methyl-n-propyl]-β-phenylethylamine hydrochloride
• Synonyms: 3,4-dibenzyloxy-N-[3-(4-benzyloxy)-1-methyl-n-propyl]-β-phenylethylamine hydrochloride
• CAS NO: 1020073-90-8
• Molecular Weight: 608.22
• Mol File: 1020073-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-dibenzyloxy-N-[3-(4-benzyloxy)-1-methyl-n-propyl]-β-phenylethylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dibenzyloxy-N-[3-(4-benzyloxy)-1-methyl-n-propyl]-β-phenylethylamine hydrochloride(1020073-90-8)
• EPA Substance Registry System: 3,4-dibenzyloxy-N-[3-(4-benzyloxy)-1-methyl-n-propyl]-β-phenylethylamine hydrochloride(1020073-90-8)

Safety Data

• Hazardous Substances Data: 1020073-90-8(Hazardous Substances Data)

Upstream product

• 74432-58-9 4-(4-(benzyloxy)phenyl)butan-2-one 
• 55536-65-7 3,4-di(benzyloxy)phenethylamine 

Downstream Products

• 34368-04-2 dobutamine 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF 4-[2-[[3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]AMINO]ETHYL]-1,2-BENZENEDIOL

The present invention relates to a process for the preparation of 4-[2-[[3-(4-hydroxyphenyl)-1- rnethylpropyl]amino]ethyl]-1,2-benzenediol, a compound of formula (I), and its pharmaceutically acceptable salts. The compound of formula (I), commonly known as dobutamine, is used in therapy as a cardiotonic for treating cardiac insufficiency. The process for preparation of a compound of formula (I) or its pharmaceutically acceptable salts comprises subjecting 3,4-bis(arylmethyloxy)-N-[3-(4-arylmethyloxy)-1 -methylpropyl]-β- phenethyl amine, a compound of formula (V), wherein R is independently selected from hydrogen, (C1-C6)alkyl, O-(C1-C6)-alkyl, aryl, O-aryl, aralkyl, halogen and hydroxyl, to catalytic hydrogenolysis.