1020083-84-4Relevant articles and documents
Palladium-Catalyzed Aminomethylamination and Aromatization of Aminoalkenes with Aminals via C-N Bond Activation
Li, Lixin,Liu, Peipei,Su, Yijin,Huang, Hanmin
, p. 5736 - 5739 (2016)
Thanks to the facile imine-enamine tautomerization, the β,γ-unsaturated hydrazones have been successfully utilized as surrogates of aminodienes for realizing the Pd-catalyzed tandem aminomethylamination/aromatization reaction with aminals via C-N bond activation. This direct and operationally simple protocol provides a fundamentally novel strategy to synthesize aromatic heterocycles from alkenes in the absence of external oxidant and base. Mechanistic studies suggested that aminal not only functioned as an aminomethyl source but also acted as formal oxidant and inner base to promote the aromatization.
RCM-mediated synthesis of fluorinated cyclic hydrazines
De Matteis, Valeria,Van Delft, Floris L.,Tiebes, J?rg,Rutjes, Floris P. J. T.
, p. 351 - 354 (2008/09/16)
A series of fluorinated cyclic hydrazine derivatives has been prepared in a straightforward manner using ring-closing metathesis (RCM) of fluorinated- and trifluoromethylated olefins as the key step. Georg Thieme Verlag Stuttgart.
