102070-03-1Relevant articles and documents
Calcite and fluorite as catalyst for the Kn?venagel condensation of malononitrile and methyl cyanoacetate under solvent-free conditions
Wada, Shinobu,Suzuki, Hitomi
, p. 399 - 401 (2003)
When milled together with calcite or fluorite, malononitrile and methyl cyanoacetate readily underwent Kn?venagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α-cyanocinnamic esters in good to excellent yi
Versatile CuI/Pd0 dual catalysis for the synthesis of quaternary α-allylated carbonyl compounds: Development, mechanistic investigations and scope
Nahra, Fady,Mace, Yohan,Boreux, Arnaud,Billard, Francois,Riant, Olivier
supporting information, p. 10970 - 10981 (2014/09/17)
We report herein a versatile cooperative dual catalysis reaction based on a CuI/Pd0 system. Mechanistic investigation shows that every component plays a crucial role in determining the reaction outcome. The reaction is successfully extended to various substrates; such as α,β-unsaturated ketones, malonates and coumarins. The strategy tolerates different substitution patterns and affords good yields for each family of substrates.
CATALYSIS OF THE KNOEVENAGEL CONDENSATION.
Chalais, Stephane,Laszlo, Pierre,Mathy, Arthur
, p. 4453 - 4454 (2007/10/02)
Xonotlite alone or made more basic by doping of potassium t-butoxide catalyses the title reaction between aromatic aldehydes and malononitrile or alkyl cyanoacetates.At ambient temperatures, this procedure specifically gives high yields of E olefinic Knoe
