102120-87-6 Usage
Description
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE, also known as Ibuprofen EP Impurity R, is an organic compound that serves as an impurity in the synthesis of Ibuprofen. It is characterized by its molecular structure, which consists of an ethane core with two 4-isobutylphenyl groups attached to the 1,1-positions. 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE exhibits selective cyclooxygenase inhibitory activity, with an IC50 value of 14.9 μM, and inhibits both PGH synthase-1 and PGH synthase-2 with comparable potency.
Uses
Used in Pharmaceutical Industry:
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE is used as an impurity in the synthesis of Ibuprofen (I140000), a widely used nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is known for its analgesic, antipyretic, and anti-inflammatory properties, making it a common choice for treating various conditions such as headaches, muscle pain, menstrual cramps, and arthritis.
As a selective cyclooxygenase inhibitor, 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE may also have potential applications in the development of new drugs targeting the cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins and other eicosanoids involved in inflammation and pain.
Check Digit Verification of cas no
The CAS Registry Mumber 102120-87-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,1,2 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 102120-87:
(8*1)+(7*0)+(6*2)+(5*1)+(4*2)+(3*0)+(2*8)+(1*7)=56
56 % 10 = 6
So 102120-87-6 is a valid CAS Registry Number.
