102130-84-7 Usage
Description
Nemadectin, a potent antiparasitic macrolide lactone, is a fermentation product of Streptomyces cyaneogriseus noncyanogenus. Structurally, it lacks a disaccharide group at C-13 and contains a trisubstituted double bond at C-26 in its side chains, distinguishing it from the milbemycins proper.
Uses
Used in Veterinary Medicine:
Nemadectin is used as an antiparasitic agent for the treatment and control of various nematode and arthropod parasites in livestock and companion animals. Its pronounced nematocidal and insecticidal activity makes it effective against a wide range of parasites, including gastrointestinal worms, lungworms, and mites.
Used in Pharmaceutical Industry:
Nemadectin serves as the starting material for moxidectin, a commercial anthelmintic used in human and veterinary medicine. Moxidectin exhibits potent nematocidal and insecticidal activity, making it a valuable asset in the treatment of parasitic infections in both humans and animals.
Check Digit Verification of cas no
The CAS Registry Mumber 102130-84-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,1,3 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 102130-84:
(8*1)+(7*0)+(6*2)+(5*1)+(4*3)+(3*0)+(2*8)+(1*4)=57
57 % 10 = 7
So 102130-84-7 is a valid CAS Registry Number.
InChI:InChI=1/C36H52O8/c1-20(2)13-24(6)32-25(7)30(37)18-35(44-32)17-28-16-27(43-35)12-11-22(4)14-21(3)9-8-10-26-19-41-33-31(38)23(5)15-29(34(39)42-28)36(26,33)40/h8-11,13,15,20-21,25,27-33,37-38,40H,12,14,16-19H2,1-7H3/b9-8+,22-11+,24-13+,26-10+/t21-,25-,27+,28-,29-,30-,31+,32+,33+,35-,36+/m0/s1
102130-84-7Relevant articles and documents
A process for preparing high-content loni mork sandbank method
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, (2017/08/26)
The invention discloses a method for preparing high-content nemadectin and belongs to the technical field of organic chemistry. According to the method, crystallized and purified 5-O (protecting group)-23-Oxo nemadectin or 5-O (protecting group)-23-formaldoxime nemadectin is taken as the raw material, and the high-content nemadectin is obtained through deoximation, reduction, deprotection and silicagel column separation; the HPLC purity of the obtained nemadectin is larger than or equal to 95.0A%, and content is larger than or equal to 93.0wt.%. The method has the advantages that aftertreatment is easy, column separation frequency is low, and nemadectin content is high.
