1021305-94-1Relevant articles and documents
An efficient 1,2-chelation-controlled reduction of protected hydroxy ketones via Red-Al
Bajwa, Naval,Jennings, Michael P.
, p. 3638 - 3641 (2008/09/20)
(Chemical Equation Presented) In this paper, we have demonstrated that Red-Al is an efficient chelation-controlled reducing reagent for acyclic acetal (i.e., MOM, MEM, SEM, and BOM) protected α-hydroxy ketones. Typically, diastereomeric ratios (dr) ranged from 5 to 20:1 for the 1,2-anti-diols in good to excellent yields.