1021397-34-1

Basic information

• Product Name: N-(3-bromo-4-methylphenyl)-2-(trifluoromethyl)benzamidine
• Synonyms: N-(3-bromo-4-methylphenyl)-2-(trifluoromethyl)benzamidine
• CAS NO: 1021397-34-1
• Molecular Weight: 357.173
• Mol File: 1021397-34-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-bromo-4-methylphenyl)-2-(trifluoromethyl)benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-bromo-4-methylphenyl)-2-(trifluoromethyl)benzamidine(1021397-34-1)
• EPA Substance Registry System: N-(3-bromo-4-methylphenyl)-2-(trifluoromethyl)benzamidine(1021397-34-1)

Safety Data

• Hazardous Substances Data: 1021397-34-1(Hazardous Substances Data)

Upstream product

• 7745-91-7 3-bromo-4-methylaniline 
• 447-60-9 2-(trifluoromethyl)benzonitrile 

Relevant articles and documents

C-H functionalization/C-N bond formation: Copper-catalyzed synthesis of benzimidazoles from amidines

(Chemical Equation Presented) Copper closes the ring: Benzimidazoles are synthesized from amidines through a copper-catalyzed C-H functionalization/ C-N bond-forming process. The method tolerates a broad range of functional groups and provides the benzimidazoles in up to 89% yield. Best results are obtained by using 15 mol% Cu(OAc)2, 2-5 equivalents of HOAc as additive, and oxygen as the stoichiometric reoxidant (see scheme).