1021949-54-1

Basic information

• Product Name: 1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-amine
• Synonyms: 1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-amine
• CAS NO: 1021949-54-1
• Molecular Weight: 264.33
• Mol File: 1021949-54-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-amine(1021949-54-1)
• EPA Substance Registry System: 1-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-4-amine(1021949-54-1)

Safety Data

• Hazardous Substances Data: 1021949-54-1(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 5334-43-0 5-Amino-4-cyano-1-phenylpyrazole 
• 108-94-1 cyclohexanone 

Relevant articles and documents

Synthesis and biological evaluation of new tacrine analogues under microwave irradiation

Efficient routes to various kinds of heterocycles incorporating the p-halophenyl moiety have been synthesized. Different pyrrole derivatives have been synthesized, as well, by Thorpe–Ziegler cyclization. Therefore, we synthesized different analogues of tacrine by Friedl?nder reaction of o-amino nitriles (pyrazolo, furano and pyrrolo) with different cycloalkanones. The use of microwave irradiation leads to shorter production times and high product conversion. These synthesized compounds were biologically evaluated by Ellman’s test on acetylcholinesterase inhibition.

Simultaneous synthesis of pyrazolopyridines and pyrazolopyrimidinones under microwave irradiation

The direct reaction of o-aminopyrazocarbonitriles and carbonyl compounds to afford pyrazolopyrimidinones was discovered; hence, a simultaneous synthetic method for pyrazolopyridines and pyrazolopyrimidinones was achieved. Under microwave irradiation, bett