1023815-74-8

Basic information

• Product Name: (3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate
• Synonyms: (3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate;(3,3-Dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl} cyclobutyl)methyl 4-methylbenzene-1-sulfonate - D4463;1,1-bis-(Toluene-4-sulfonyloxymethyl)-3,3-dimethoxy-cyclobutane;(1-hydroxymethyl-3,3-dimethoxycyclobutyl)methanol bisp-toluenesulfonate;1,1-Cyclobutanedimethanol, 3,3-dimethoxy-, 1,1-bis(4-methylbenzenesulfonate)
• CAS NO: 1023815-74-8
• Molecular Formula: C₂₂H₂₈O₈S₂
• Molecular Weight: 484.58292
• Mol File: 1023815-74-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate(1023815-74-8)
• EPA Substance Registry System: (3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate(1023815-74-8)

Safety Data

• Hazardous Substances Data: 1023815-74-8(Hazardous Substances Data)

Usage

General Description

The chemical "(3,3-dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate" is a complex organic compound with a cyclobutylmethyl group attached to a 4-methylbenzene-1-sulfonate. It has two methoxy groups and a sulfonyloxy group attached to the cyclobutylmethyl group, and a methyl group attached to the benzene ring. This chemical likely has specific applications in organic synthesis or pharmaceuticals due to its unique structure and functional groups. It may also have potential uses in medicinal chemistry or drug development.

Upstream product

• 115118-68-8 3,3-dimethoxycyclobutane-1,1-dicarboxylic acid diisopropyl ester 
• 130369-33-4 (1-hydroxymethyl-3,3-dimethoxycyclobutyl)methanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1118786-87-0 6,6-dimethoxy-spiro[3.3]heptane-2,2-dicarboxylic acid diisopropyl ester 
• 1398571-15-7 Ethyl (3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-3,3-bis(fluoromethyl)-2-oxo-1,2-dihydrodispiro[cyclobutane-1,2'-pyrrolidine-3',3-indole]-5'-carboxylate 

Relevant articles and documents

SPIRO COMPOUND AS INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR

Disclosed in the present invention are an indoleamine-2,3-dioxygenase inhibitor and a preparation method therefor. The inhibitor of the present invention has a structure as represented by general formula (I), wherein the definitions of Ar, E, Y, X, V, D, W, B, ring A and ring B are as shown in the description and claims. Also disclosed in the present invention is a preparation method for the inhibitor. The compound of general formula (I) of the present invention can be used as an indoleamine-2,3-dioxygenase inhibitor for preparing a medicament for preventing and/or treating indoleamine-2,3-dioxygenase-mediated diseases.

Synthesis of conformationally restricted glutamic acid analogs based on the spiro[3.3]heptane scaffold

A library of isomeric glutamic acid analogs based on the spiro[3.3]heptane skeleton is designed. Two members of the library, (R)- and (S)-2-amino-spiro[3.3]heptane-2,6-dicarboxylic acid hydrochlorides, were synthesized. The stereochemistry of the synthesi