10242-00-9 Usage
Description
6-NITRO-1H-INDOLE-2-CARBOXYLIC ACID is an organic compound with the molecular formula C9H6N2O4. It is a key intermediate in the synthesis of various heterocyclic compounds, particularly those with potential applications in the pharmaceutical industry. Its chemical structure features a nitro group at the 6th position of the indole ring and a carboxylic acid group at the 2nd position, which contribute to its reactivity and utility in chemical synthesis.
Uses
Used in Pharmaceutical Industry:
6-NITRO-1H-INDOLE-2-CARBOXYLIC ACID is used as a key intermediate for the synthesis of oxazoles, triazoles, and related heterocycles. These heterocyclic compounds have been identified as mitochondrial activity inhibitors, which can be employed in the treatment of various types of cancers. By targeting mitochondrial activity, these compounds can disrupt cellular processes and inhibit tumor growth, making them valuable tools in the development of novel anticancer therapies.
In the preparation of these bioactive heterocycles, 6-NITRO-1H-INDOLE-2-CARBOXYLIC ACID serves as a versatile building block, allowing for the creation of a diverse range of compounds with potential therapeutic applications. Its use in the pharmaceutical industry is primarily focused on the development of new drugs for cancer treatment, leveraging its ability to form various heterocyclic structures with biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 10242-00-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,4 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 10242-00:
(7*1)+(6*0)+(5*2)+(4*4)+(3*2)+(2*0)+(1*0)=39
39 % 10 = 9
So 10242-00-9 is a valid CAS Registry Number.
10242-00-9Relevant articles and documents
Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases
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Paragraph 0399; 0402, (2015/09/22)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES
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, (2012/04/23)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
Novel aromatic compounds possessing antifungal or antibacterial activity
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Page/Page column 46; 65, (2010/02/06)
The present invention provides novel compounds possessing antibacterial, antifungal, antiviral, anticancer, and/or antiparasitic activities. Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds ar
