102451-67-2

Basic information

• Product Name: 3-[1-(4-chlorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
• Synonyms: 3-[1-(4-chlorophenyl)-2-nitroethyl]-2-phenyl-1H-indole
• CAS NO: 102451-67-2
• Molecular Weight: 376.842
• Mol File: 102451-67-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-[1-(4-chlorophenyl)-2-nitroethyl]-2-phenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1-(4-chlorophenyl)-2-nitroethyl]-2-phenyl-1H-indole(102451-67-2)
• EPA Substance Registry System: 3-[1-(4-chlorophenyl)-2-nitroethyl]-2-phenyl-1H-indole(102451-67-2)

Safety Data

• Hazardous Substances Data: 102451-67-2(Hazardous Substances Data)

Upstream product

• 948-65-2 2-phenyl-indole 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 
• 13141-38-3 2-phenylethynylaniline 
• 583-11-9 N-(1-phenylethylidene)phenylhydrazine 

Relevant articles and documents

Synthesis of Spiro[indole-3,5′-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles

An acid-assisted [4 + 1]-cycloaddition of indoles with nitrostyrenes affords 4′H-spiro[indole-3,5′-isoxazoles] in a diastereomerically pure form. Several of these spirocyclic molecules exhibit promising anticancer activity by reducing viability and inducing differentiation of neuroblastoma cells.

Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility

Specific tuning of cannabinoid 1 receptor (CB1R) activity by small-molecule allosteric modulators is a therapeutic modality with multiple properties inherently advantageous to therapeutic applications. We previously generated a library of unique CB1R posi