102493-68-5

Basic information

• Product Name: 2-(2-Chloro-6-nitrophenyl)ethanol
• Synonyms: 2-(2-Chloro-6-nitrophenyl)ethanol;MFCD00239018
• CAS NO: 102493-68-5
• Molecular Formula: C₈H₈ClNO₃
• Molecular Weight: 201.60702
• Mol File: 102493-68-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 311.4°Cat760mmHg
• Flash Point: 142.1°C
• Appearance: /
• Density: 1.404g/cm³
• Vapor Pressure: 0.000242mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2-Chloro-6-nitrophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Chloro-6-nitrophenyl)ethanol(102493-68-5)
• EPA Substance Registry System: 2-(2-Chloro-6-nitrophenyl)ethanol(102493-68-5)

Safety Data

• Hazardous Substances Data: 102493-68-5(Hazardous Substances Data)

Usage

Uses

2-(2-Chloro-6-nitrophenyl)ethanol is a useful research chemical compound.

InChI:InChI=1/C8H8ClNO3/c9-7-2-1-3-8(10(12)13)6(7)4-5-11/h1-3,11H,4-5H2

Upstream product

• 83-42-1 6-chloro-2-nitrotoluene 
• 100-85-6 N-benzyl-trimethylammonium hydroxide 
• 31912-08-0 (2-chloro-6-nitro-phenyl)-acetic acid 
• 50-00-0 formaldehyd 

Downstream Products

• 122509-63-1 2-(2'-chloro-6'-nitrophenyl)acetaldehyde 
• 100376-53-2 2-(2-amino-6-chlorophenyl)ethyl alcohol 
• 620964-59-2 2-(2-bromo-ethyl)-1-chloro-3-nitro-benzene 
• 27542-41-2 4-chloro-D-tryptophan 
• 27542-41-2 (S)-2-amino-3-(4-chloro-1H-indol-3-yl)propanoic acid 
• 118244-93-2 4-chloro-DL-tryptophan 
• 25235-85-2 4-chloro-1H-indole 
• 102493-80-1 N-benzyl-4-chloro-5-(2-nitrobuten-1-yl)-2,3-dihydroindole 
• 102493-72-1 N-benzyl-4-chloro-5-(2-nitropropen-1-yl)-2,3-dihydroindole 
• 102493-81-2 1-(1-Benzyl-4-chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propylamine 
• 102493-73-2 2-(1-Benzyl-4-chloro-2,3-dihydro-1H-indol-5-yl)-1-methyl-ethylamine 
• 102493-71-0 N-benzyl-4-chloro-2,3-dihydroindole-5-carboxaldehyde 
• 102493-70-9 N-benzyl-4-chloro-2,3-dihydroindole 
• 41910-64-9 4-chloroindoline 

Relevant articles and documents

Pd-tBuONO Cocatalyzed Aerobic Indole Synthesis

A Pd-tBuONO co-catalyzed scalable and practical synthesis of indoles with molecular oxygen as terminal oxidant is developed. Either terminal or internal 2-vinylanilines could be smoothly converted to desired indoles under one general condition. This method has been evaluated in the large scale synthesis of indomethacin and a potential anti-breast cancer drug candidate 1. (Figure presented.).

Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles

A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.

[1,4]DIAZOCINO [7,8,1-hi]INDOLE DERIVATIVES AS ANTIPSYCHOTIC AND ANTIOBESITY AGENTS

Compounds of formula (1) are provided: (1) where R1 through R7 are defined herein. The compounds of formula (I) are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.