1024982-27-1

Basic information

• Product Name: C₈₅H₁₃₂N₁₂O₄₇S₂
• Synonyms: C₈₅H₁₃₂N₁₂O₄₇S₂
• CAS NO: 1024982-27-1
• Molecular Weight: 2138.17
• Mol File: 1024982-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈₅H₁₃₂N₁₂O₄₇S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₈₅H₁₃₂N₁₂O₄₇S₂(1024982-27-1)
• EPA Substance Registry System: C₈₅H₁₃₂N₁₂O₄₇S₂(1024982-27-1)

Safety Data

• Hazardous Substances Data: 1024982-27-1(Hazardous Substances Data)

Upstream product

• 50-56-6 oxytocin 
• 769884-11-9 mono-6-deoxy-6-carboxy-β-cyclodextrin 

Relevant articles and documents

Synthesis and pharmacological evaluation of a new targeted drug carrier system: β-Cyclodextrin coupled to oxytocin

β-Cyclodextrin (β-CD) was monofunctionalized into its carboxylic derivative and then conjugated to the N-side of oxytocin (OT), a nonapeptide involved in human behavior and myometrium contraction. On isolated rat myometrium, this conjugate (β-CD-OT) partly preserves the contracting activity of OT (EC50 = 0.40 μM vs 1.7 nM). Moreover, the contraction induced frequency is also lowered by β-CD-OT. This novel hydrophilic targeted carrier could form a host-guest complex with prostaglandins and their derivatives used as labor inducers or with anticancer drugs used in cervix and endometrial cancer. This strategy can improve the solubility, the stability, and/or the biological activity of these drugs as well as reducing their side-effects.