102540-16-9

Basic information

• Product Name: α-acetoxy-2-bromoacetophenone
• Synonyms: α-acetoxy-2-bromoacetophenone
• CAS NO: 102540-16-9
• Molecular Weight: 257.084
• Mol File: 102540-16-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-acetoxy-2-bromoacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: α-acetoxy-2-bromoacetophenone(102540-16-9)
• EPA Substance Registry System: α-acetoxy-2-bromoacetophenone(102540-16-9)

Safety Data

• Hazardous Substances Data: 102540-16-9(Hazardous Substances Data)

Upstream product

• 75-75-2 methanesulfonic acid 
• 766-46-1 2-bromo-1-ethynylbenzene 
• 64-19-7 acetic acid 
• 583-55-1 1-Bromo-2-iodobenzene 
• 13831-31-7 Acetoxyacetyl chloride 

Downstream Products

• 99233-20-2 α-hydroxy-2-bromoacetophenone 

Relevant articles and documents

Decarboxylative Oxyacyloxylation of Propiolic Acids: Construction of Alkynyl-Containing α-Acyloxy Ketones

Novel decarboxylative oxyacyloxylation of propiolic acids has been developed. This reaction provides an efficient access to alkynyl-containing α-acyloxy ketones from readily available starting materials and exhibits significant functional group tolerance. Furthermore, oxyacyloxylation of terminal alkynes and aliphatic propiolic acids was also developed. A possible reaction mechanism is proposed based on mechanistic studies.

Synthesis of α-hydroxyacetophenones

A general method for the preparation of α-hydroxyacetophenones is presented. Functionalized arylmagnesium species are transmetalated to the corresponding arylzinc intermediates, which undergo Cu(I)-catalyzed reaction with acetoxyacetyl chloride. Acidic hy