1025437-79-9

Basic information

• Product Name: (2R)-N-[(S)-3-dimethylamino-1-(2-naphthyl)propyl]-2-methoxy-2-phenylacetamide
• CAS NO: 1025437-79-9
• Molecular Weight: 376.499
• Mol File: 1025437-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-N-[(S)-3-dimethylamino-1-(2-naphthyl)propyl]-2-methoxy-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-N-[(S)-3-dimethylamino-1-(2-naphthyl)propyl]-2-methoxy-2-phenylacetamide(1025437-79-9)
• EPA Substance Registry System: (2R)-N-[(S)-3-dimethylamino-1-(2-naphthyl)propyl]-2-methoxy-2-phenylacetamide(1025437-79-9)

Safety Data

• Hazardous Substances Data: 1025437-79-9(Hazardous Substances Data)

Upstream product

• 917351-50-9 3-dimethylamino-1-(2-naphthyl)propanamine 
• 3966-32-3 (R)-methoxyphenylacetic acid 

Relevant articles and documents

Novel and potent small-molecule urotensin II receptor agonists

A series of analogs of the non-peptidic urotensin II receptor agonist N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-4-phenylbenzamide (FL104) has been synthesized and evaluated pharmacologically. The enantiomers of the two most potent racemic analogues were obtained from the corresponding diastereomeric mandelic amides. In agreement with previously observed SAR, most of the agonist potency resided in the (S) enantiomers. The most potent UII receptor agonist in the new series was (S)-N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(4-chlorophenyl)benzamide (EC50 = 23 nM at the urotensin II receptor).