1026161-82-9

Basic information

• Product Name: N-[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethyl]-4-phenyl-butyramide
• CAS NO: 1026161-82-9
• Molecular Weight: 406.319
• Mol File: 1026161-82-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethyl]-4-phenyl-butyramide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethyl]-4-phenyl-butyramide(1026161-82-9)
• EPA Substance Registry System: N-[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethyl]-4-phenyl-butyramide(1026161-82-9)

Safety Data

• Hazardous Substances Data: 1026161-82-9(Hazardous Substances Data)

Upstream product

• 1821-12-1 4-Phenylbutyric acid 
• 66142-81-2 2-(4-bromo-2,5-dimethoxyphenyl)-1-aminoethane 

Relevant articles and documents

Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines

The effect of 15 different amine substituents on 5-HT2A and 5-HT2C serotonin receptor binding was investigated for two series of compounds (i.e., phenylalkylamine and indolylalkylamine derivatives). In general, amine substitution decreases receptor affinity; however, N-(4-bromobenzyl) substitution results in compounds that bind at 5-HT2A receptors with high affinity (K(i) 100-fold selectivity. Although parallel structural modifications in the two series result in parallel shifts in 5- HT2C binding, these same modifications alter 5-HT2A binding in a less consistent manner.