1026394-81-9

Basic information

• Product Name: C₂₀H₂₁Cl₂N₃O
• CAS NO: 1026394-81-9
• Molecular Weight: 390.312
• Mol File: 1026394-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₁Cl₂N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₁Cl₂N₃O(1026394-81-9)
• EPA Substance Registry System: C₂₀H₂₁Cl₂N₃O(1026394-81-9)

Safety Data

• Hazardous Substances Data: 1026394-81-9(Hazardous Substances Data)

Upstream product

• 131747-55-2 2-fluoro-3-(hydroxymethyl)pyridine 
• 1318800-53-1 C₁₂H₂₃N₃OSi 
• 1318800-61-1 C₂₀H₃₃N₃OSi 
• 1318800-56-4 C₂₀H₃₅N₃O₂Si 
• 1339959-60-2 C₁₂H₂₀FNOSi 

Relevant articles and documents

Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

A series of pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 were modified to incorporate a novel 1,2,4-triazolopyridine scaffold. Optimization of substituents at the 3 and 8 position of the TZP core, with a special focus on enhancing metabolic stability, resulted in the identification of compound 38 as a potent and metabolically stable inhibitor of the enzyme.