102645-35-2

Basic information

• Product Name: 2,5-Dichloroisonicotinonitrile
• Synonyms: 2,5-Dichloroisonicotinonitrile;2,5-Dichloropyridine-4-carbonitrile, 4-Cyano-2,5-dichloropyridine;2,5-Dichloro-4-pyridinecarbonitrile;4-Pyridinecarbonitrile, 2,5-dichloro-
• CAS NO: 102645-35-2
• Molecular Formula: C₆H₂Cl₂N₂
• Molecular Weight: 172.99948
• Mol File: 102645-35-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,5-Dichloroisonicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dichloroisonicotinonitrile(102645-35-2)
• EPA Substance Registry System: 2,5-Dichloroisonicotinonitrile(102645-35-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 102645-35-2(Hazardous Substances Data)

Usage

General Description

2,5-Dichloroisonicotinonitrile is a chemical compound with molecular formula C7H3Cl2N3. Primarily serving as an intermediate in organic synthesis, it is used in the production of various pharmaceutical drugs and chemicals. This substance is a derivative of isonicotinonitrile, which implies its role in the synthesis of isonicotinic acid derivatives. 2,5-Dichloroisonicotinonitrile is characterized by the presence of dichloro-groups and a nitrile-group, contributing to its reactivity. Its handling and storage require stringent safety measures due to potential health hazards upon exposure.

Upstream product

• 102645-34-1 C₆H₄Cl₂N₂O 
• 75-09-2 dichloromethane 
• 7440-44-0 pyrographite 

Downstream Products

• 439290-93-4 5-phenyl-1H-pyrazolo[3,4-c]pyridin-3-ylamine 

Relevant articles and documents

2-Amino-5-aryl-pyridines as selective CB2 agonists: Synthesis and investigation of structure-activity relationships

2-Amino-5-aryl-pyridines, exemplified by compound 1, had been identified as a synthetically tractable series of CB2 agonists from a high-throughput screen of the GlaxoSmithKline compound collection. Described herein are the results of an investigation of the structure-activity relationships (SAR) which led to the identification a number of potent and selective agonists.

Certain phenoxy-pyridine-carbonitriles having antiviral activity

Substituted pyridines exhibiting antiviral activity are disclosed. Also disclosed are methods of use involving the substituted pyridines as well as compositions comprising a non-toxic, pharmaceutically-acceptable carrier in combination with one or more said substituted pyridines.