10265-83-5Relevant articles and documents
Nanocrystalline aluminium oxide: A mild and efficient reusable catalyst for the one-pot synthesis of poly-substituted quinolines via Friedlander hetero-annulation
Sadjadi, Sodeh,Shiri, Soudeh,Hekmatshoar, Rahim,Beheshtiha, Yahya S.
, p. 1343 - 1347 (2009)
o-Aminoaryl ketones undergo smooth condensation with α-methylene ketones in the presence of nanocrystalline aluminium oxide under mild reaction conditions to afford the corresponding poly-substituted quinolines in excellent yields. The catalyst can be rec
Water mediated synthesis of substituted quinolines - A new green approach to the Friedlaender annulation
Selvam, Nagarajan Panneer,Saravanan, Chandramathi,Muralidharan,Perumal, Paramasivan T.
, p. 1379 - 1382 (2006)
A new green approach to the Friedlaender Quinoline synthesis is described for the preparation of polysubstituted quinolines from o-amino aryl ketones and carbonyl compounds containing active methylene group mediated by water and catalysed by KHSO4/s
A simple, efficient and solvent-free protocol for the friedlaender synthesis of quinolines by using SnCl2·2H2O
Arumugam, Pandurangan,Karthikeyan, Ganesan,Atchudan, Raji,Muralidharan,Perumal, Paramasivan T.
, p. 314 - 315 (2005)
A variety of polysubstituted quinolines have been synthesized under solvent free condition by using tin(II) chloride-dihydrate. The reaction proceeds smoothly at room temperature in short reaction time. The yields and purity are excellent. Copyright
Efficient and rapid Friedlander synthesis of functionalized quinolines catalyzed by neodymium(III) nitrate hexahydrate
Varala, Ravi,Enugala, Ramu,Adapa, Srinivas R.
, p. 3825 - 3830 (2006)
Friedlander synthesis of quinolines catalyzed by neodymium nitrate [Nd(NO3)3·6H2O, 5 mol%] in ethanol at room temperature was achieved in moderate to excellent yields (62-94%). Georg Thieme Verlag Stuttgart.
Solid-Phase Friedl?nder Synthesis Using an Alkoxyamine Linker
Yamaguchi, Kota,Noda, Takeshi,Tomizawa, Toshiki,Kanai, Eriko,Hioki, Hideaki
, p. 4990 - 4995 (2015)
A quinoline library was prepared by combinatorial synthesis using an alkoxyamine linker. Substrates were loaded onto a solid support containing an oxime linkage. After selected reactions on the solid support, the products were cleaved by a Friedl?nder-typ
Iron(III) chloride-promoted, solvent-free, facile, and efficient Friedlaender synthesis of quinolines
Kumar, Sanjay,Saini, Anil,Sandhu, Jagir S.
, p. 4071 - 4078 (2007)
A mild, efficient, and solvent-free version of Friedlaender annulation of 2-amino ketones and α-methylene carbonyl compounds for the synthesis of polysubstituted quinolines using a catalytic amount of commercially available iron(III) chloride at room temp
Nickel nanoparticles: A highly efficient and retrievable catalyst for the solventless Friedlander annulation of quinolines and their in silico molecular docking studies as histone deacetylase inhibitors
Angajala, Gangadhara,Subashini, Radhakrishnan
, p. 45599 - 45610 (2015)
The present work explores a highly efficient, environmental friendly, green, solvent-free protocol for the preparation of polysubstituted quinolines via Friedlander annulation using nickel nanoparticles (80-100 nm) biofabricated from Aegle Marmelos Correa
Magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid as a highly efficient and green heterogeneous catalyst for the synthesis of substituted quinolines and 1-amidoalkyl-2-naphthol derivatives
Katheriya, Deepak,Patel, Nipun,Dadhania, Harsh,Dadhania, Abhishek
, p. 805 - 816 (2020/10/02)
Abstract: Magnetically retrievable, magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid (DDBSA@MNP) was synthesized and characterized through different analytical techniques such as TEM, XRD, FTIR, TGA, SEM, EDX and
Pincerlike manganese complex and preparation method thereof, related ligand and preparation method thereof, catalyst composition and application
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Paragraph 0152-0158, (2021/07/31)
The invention discloses a pincerlike manganese complex, a preparation method thereof, a ligand for preparation, a preparation method of the ligand, a catalyst composition taking the complex as an active component and application of the catalyst composition. According to the pincerlike manganese complex, a cycloalkyl ring is introduced into a ligand framework, and by regulating and controlling the cyclic tension, flexibility and steric hindrance of the cycloalkyl ring, the reactivity and stability of the manganese metal center can be effectively adjusted, and the catalytic activity and substrate applicability of a manganese metal system are remarkably improved. The catalyst composition taking the pincerlike manganese complex as an active component has the advantages of high catalyst activity, wide substrate application range, mild reaction conditions and the like in the process of preparing quinoline or pyridine derivatives by catalyzing dehydrogenation coupling reaction of o-amino aromatic alcohol or gamma-amino alcohol, ketone or secondary alcohol; and the synthesis advantages of low cost and stable performance are embodied, the operation is simple, and the yield is high.
Rapid and Efficient Microwave-Assisted Friedl?nder Quinoline Synthesis
Bailey, Helen V.,Mahon, Mary F.,Vicker, Nigel,Potter, Barry V. L.
, p. 1113 - 1122 (2020/12/03)
A microwave-based methodology facilitates reaction of 2-aminophenylketones with cyclic ketones to form a quinoline scaffold. Syntheses of amido- and amino-linked 17β-hydroxysteroid dehydrogenase type 3 inhibitors with a benzophenone-linked motif were purs
