1026596-65-5

Basic information

• Product Name: C₃₈H₄₉⁽²⁾H₅N₄O₆
• CAS NO: 1026596-65-5
• Molecular Weight: 667.83
• Mol File: 1026596-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₈H₄₉⁽²⁾H₅N₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₈H₄₉⁽²⁾H₅N₄O₆(1026596-65-5)
• EPA Substance Registry System: C₃₈H₄₉⁽²⁾H₅N₄O₆(1026596-65-5)

Safety Data

• Hazardous Substances Data: 1026596-65-5(Hazardous Substances Data)

Upstream product

• 150323-35-6 t-butyl (S)-3-(tert-butylcarbamoyl)-piperazine-1-carboxylate 

Relevant articles and documents

Isotope labeled 'HEA/HEE' moiety in the synthesis of labeled HIV-protease inhibitors - Part II

[2H5]-Amprenavir and [2H 5]-saquinavir have been prepared from a common labeled precursor (1S, 2S)-(1-oxiranyl-2-[2H5]phenylethyl)-carbamic acid tert-butyl ester, 1. Both of these compounds are in the 'HEA' class of HIV protease inhibitors. [2H5]-Indinavir, a representative of the 'HEE' group of protease inhibitors, has also been synthesized. In the case of indinavir, 1S-(2,2-dimethyl-8, 8a-dihydro-3aH-indeno-[1,2-d]-oxazol-3R-yl)-2- oxiranylmethyl-3-[2H5]phenylpropan-1-one, 11, provided the [phenyl-2H5]-HEE core structure for synthesis of the desired labeled compound. Copyright