1026640-31-2

Basic information

• Product Name: 6-Chloro-3-isocyanato-4-o-tolyl-chromen-2-one
• CAS NO: 1026640-31-2
• Molecular Weight: 311.724
• Mol File: 1026640-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Chloro-3-isocyanato-4-o-tolyl-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-3-isocyanato-4-o-tolyl-chromen-2-one(1026640-31-2)
• EPA Substance Registry System: 6-Chloro-3-isocyanato-4-o-tolyl-chromen-2-one(1026640-31-2)

Safety Data

• Hazardous Substances Data: 1026640-31-2(Hazardous Substances Data)

Upstream product

• 137711-58-1 6-chloro-4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester 
• 933-88-0 ortho-toluoyl chloride 
• 106-48-9 4-chloro-phenol 
• 52980-94-6 5-chloro-2-hydroxy-2'-methylbenzophenone 
• 500285-59-6 2-methyl-benzoic acid-(4-chloro-phenyl ester) 
• 137711-72-9 6-chloro-4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-3-carboxylic acid 

Relevant articles and documents

Synthesis of 3-ureido derivatives of coumarin and 2-quinolone as potent Acyl-CoA: Cholesterol acyltransferase inhibitors

Novel 3-ureido derivatives of 4-phenylcoumarin and 4-phenyl-2-quinolone were synthesized and evaluated for acyl-CoA: cholesterol acyltransferase (ACAT)-inhibitory activity. These derivatives inhibited rat intestinal ACAT with IC50 values at the 10-8 to 10-9 M level and were found to normalize plasma cholesterol levels in cholesterol-fed rats when administered as dietary admixtures.