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1026791-31-0

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1026791-31-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1026791-31-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,6,7,9 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1026791-31:
(9*1)+(8*0)+(7*2)+(6*6)+(5*7)+(4*9)+(3*1)+(2*3)+(1*1)=140
140 % 10 = 0
So 1026791-31-0 is a valid CAS Registry Number.

1026791-31-0Downstream Products

1026791-31-0Relevant articles and documents

The design of a novel series of muscarinic receptor antagonists leading to AZD8683, a potential inhaled treatment for COPD

Mete, Antonio,Bowers, Keith,Bull, Richard J.,Coope, Helen,Donald, David K.,Escott, Katherine J.,Ford, Rhonan,Grime, Ken,Mather, Andrew,Ray, Nicholas C.,Russell, Vince

, p. 6248 - 6253 (2013)

A novel series of muscarinic receptor antagonists was developed, with the aim of identifying a compound with high M3 receptor potency and a reduced risk of dose-limiting side effects with potential for the treatment of COPD. Initial compound mo

QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS

-

, (2009/12/23)

The invention provides named compounds of formula (I ), wherein R4 is a N- sustituted quinuclidine ( I ) pharmaceutical compositions containing them and a process for preparing the pharmaceutical compositions. Their use in therapy for' the treatment of conditions mediated by M3 muscarinic receptors, such as chronic obstructive pulmonary disease is also disclosed.

QUINICLIDINE DERIVATIVES OF (HETERO) ARYLCYCLOHEPTANECARBOXYLIC ACID AS MUSCARINIC RECEPTOR ANTAGONISTS

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Page/Page column 45-46, (2008/12/05)

The invention provides compounds of formula (I) wherein R4 is a group of formula (II) or (IIIa) or (IIIb) and R1, R2, R3, R5, a, b and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation (I), (II), (IIIa), (IIIb).

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