1026809-34-6

Basic information

• Product Name: 4-[5-(4,5,7-trimethyl-benzofuran-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester
• CAS NO: 1026809-34-6
• Molecular Weight: 359.425
• Mol File: 1026809-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[5-(4,5,7-trimethyl-benzofuran-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(4,5,7-trimethyl-benzofuran-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(1026809-34-6)
• EPA Substance Registry System: 4-[5-(4,5,7-trimethyl-benzofuran-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(1026809-34-6)

Safety Data

• Hazardous Substances Data: 1026809-34-6(Hazardous Substances Data)

Upstream product

• 289892-03-1 4,5,7-trimethylbenzofuran-2-carbaldehyde 
• 1027417-43-1 4,5,7-trimethyl-benzofuran 
• 496-78-6 2,4,5-trimethylphenol 
• 1026170-66-0 4-[4-oxo-4-(4,5,7-trimethyl-benzofuran-2-yl)-butyryl]-benzoic acid methyl ester 

Relevant articles and documents

Discovery of novel and potent retinoic acid receptor α agonists: Syntheses and evaluation of benzofuranyl-pyrrole and benzothiophenyl-pyrrole derivatives

In the course of our studies on retinoic acid receptor (RAR) agonists, we have designed and synthesized a series of benzofuran and benzothiophene derivatives. Some of these compounds (1a,b,e,f,j) markedly inhibited LPS- induced B-lymphocyte proliferation and exerted RARα selectivity. One of them, 4-[5-(4,7-dimethylbenzofuran-2-yl)pyrrol-2-yl]benzoic acid (1b), when orally administered significantly inhibited mouse antibody production and delayed type hypersensitivity (DTH) responses from a dose of 0.1 mg/kg.