1027181-89-0

Basic information

• Product Name: (2,2-Bis-phenylsulfanyl-vinyl)-(3,4-dimethoxy-benzyl)-amine
• CAS NO: 1027181-89-0
• Molecular Weight: 409.573
• Mol File: 1027181-89-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,2-Bis-phenylsulfanyl-vinyl)-(3,4-dimethoxy-benzyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-Bis-phenylsulfanyl-vinyl)-(3,4-dimethoxy-benzyl)-amine(1027181-89-0)
• EPA Substance Registry System: (2,2-Bis-phenylsulfanyl-vinyl)-(3,4-dimethoxy-benzyl)-amine(1027181-89-0)

Safety Data

• Hazardous Substances Data: 1027181-89-0(Hazardous Substances Data)

Upstream product

• 5763-61-1 3,4-dimethoxybenzylamine 
• 153823-24-6 Bis(phenylsulfanyl)acetaldehyde 

Downstream Products

• 189081-50-3 N-(2,2-Bis-phenylsulfanyl-vinyl)-2-bromo-N-(3,4-dimethoxy-benzyl)-benzamide 

Relevant articles and documents

Sulfur-controlled 5-exo selective aryl radical cyclisation of N-vinylic 2-bromobenzamides: Synthesis of lennoxamine and chilenine

Bu3SnH-mediated aryl radical cyclisation of N-[2,2-bis(phenylsulfanyl)ethenyl]-2-bromobenzamides 12a-d and 16 takes place in a 5-exo manner to give exclusively the isoindolones 15a-d and 17, respectively. The isoindolone 17 is converted into lennoxamine and a key intermediate 20 for the synthesis of chilenine.