1027422-60-1

Basic information

• Product Name: (3-{[3-(Di-tert-butyl-phosphanyl)-propyl]-phenyl-phosphanyl}-phenyl)-trimethylsilanyl-amine
• CAS NO: 1027422-60-1
• Molecular Weight: 459.667
• Mol File: 1027422-60-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-{[3-(Di-tert-butyl-phosphanyl)-propyl]-phenyl-phosphanyl}-phenyl)-trimethylsilanyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3-{[3-(Di-tert-butyl-phosphanyl)-propyl]-phenyl-phosphanyl}-phenyl)-trimethylsilanyl-amine(1027422-60-1)
• EPA Substance Registry System: (3-{[3-(Di-tert-butyl-phosphanyl)-propyl]-phenyl-phosphanyl}-phenyl)-trimethylsilanyl-amine(1027422-60-1)

Safety Data

• Hazardous Substances Data: 1027422-60-1(Hazardous Substances Data)

Upstream product

• 42491-34-9 di-tert-butyl(trimethylsilyl)phosphane 
• 142132-41-0 1,1-di-tert-butylphosphetanium bromide 

Relevant articles and documents

Water Soluble Cationic Phosphine Ligands Containing m-Guanidinium Phenyl Moieties. Syntheses and Applications in Aqueous Heck Type Reactions

Cationic phosphine ligands containing m-guanidinium phenyl substituents {Ph3-nP[C6H4-m-NHC(NH2)(NMe 2)]n}n+ nCl- (n = 1-3) (17a-c) have been obtained by addition of dimethylcyanamide to the amino groups of tertiary (m-aminophenyl)phosphines in acidic medium. The tertiary (m-aminophenyl)phosphines Ph3-nP(C6H4-m-NH2)n (4a-c) were prepared by reaction of (3-[N,N-bis(trimethylsilyl)amino]phenyl)magnesium chloride (1) with chlorophosphines Ph3-nPCln followed by deprotection of the bis(trimethylsilyl)amino groups with methanol. Using a similar protected group synthesis as above, the secondary (m-aminophenyl)phosphine Ph(H)PC6H4-m-NH2 (7) could be prepared as well. It may be employed as a building block for the syntheses of chiral bidentate phosphine ligands (11, 14, and 15) bearing m-aminophenyl substituents. The guanidinium phosphines 17b and 17c are readily soluble in water. A comparative study of 17b and 17c, the aryl alkyl guanidinium phosphines 18 and 19, and TPPTS (P(C6H4-m-SO3Na)3) in the aqueous phase palladium-catalyzed C-C coupling reaction between p-iodobenzoate and (trifluoroacetyl)propar-gylamine shows 17b to be of surmounting activity.