10275-07-7

Basic information

• Product Name: Benzoquinoneacetic acid
• Synonyms: Benzoquinoneacetic acid
• CAS NO: 10275-07-7
• Molecular Formula: C₈H₆O₄
• Molecular Weight: 166.13
• Mol File: 10275-07-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 344°Cat760mmHg
• Flash Point: 176°C
• Appearance: /
• Density: 1.429g/cm³
• Vapor Pressure: 1.22E-05mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: Benzoquinoneacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoquinoneacetic acid(10275-07-7)
• EPA Substance Registry System: Benzoquinoneacetic acid(10275-07-7)

Safety Data

• Hazardous Substances Data: 10275-07-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H6O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3H,4H2,(H,11,12)

Upstream product

• 1758-25-4 (2,5-dimethoxyphenyl)acetic acid 
• 451-13-8 homogentisic acid 
• 7664-93-9 sulfuric acid 

Downstream Products

• 451-13-8 homogentisic acid 
• 1758-25-4 (2,5-dimethoxyphenyl)acetic acid 

Relevant articles and documents

Mechanisms of interference of p-diphenols with the Trinder reaction

p-Diphenols, such as homogentisic acid, gentisic acid, etamsylate, and calcium dobesilate, interfere with diagnostic tests utilizing the Trinder reaction but the mechanisms of these effects are not fully understood. We observed substantial differences both in oxidation of p-diphenols by horseradish peroxidase and their influence on oxidation of 4-aminoantipyrine and various phenolic substrates. Homogentisic acid was rapidly oxidized by the enzyme and completely blocked chromophore formation. Enzymatic oxidation of the remaining p-diphenols was slow and they only moderately inhibited chromophore formation. However, in the presence of standard substrates all tested p-diphenols were rapidly converted to p-quinones. Hydrogen peroxide consumption was significantly accelerated by homogentisic acid but not much affected by the other p-diphenols. The magnitude and mechanisms of interference caused by p-diphenols therefore depend on their structure which determines their electrochemical properties – while for homogentisic acid with an electron-donating substituent and a lower reduction potential both enzymatic oxidation and reduction of the peroxidase-generated radicals occur, for p-diphenols with electron-withdrawing substituents and higher reduction potentials only the second mechanism is significant. Correlation of the effects on the Trinder reaction with reduction potentials of interfering compounds allows prediction of such properties for a wide range of other reducing compounds based on this parameter. It also explains why compounds with very different structures but strong reducing properties show such effects.

Method for dyeing keratinous fibres using an aminoindole in combination with a quinone derivative

Method for dyeing keratinous fibres, characterized in that at least one composition (A) containing at least one aminoindole in a medium appropriate for dyeing is applied to these fibres, the application of the composition (A) being preceded or followed by the application of a composition (B) containing, in a medium appropriate for dyeing, at least one quinone derivative chosen from ortho- or para-benzoquinones, ortho- or para-benzoquinone monoimines or diimines, 1,2- or 1,4-naphthoquinones, ortho- or para-benzoquinone sulphonimides, α,ω-alkylene-bis-1,4-benzoquinones, or 1,2- or 1,4-naphthoquinone monoimines or diimines, the aminoindoles and the quinone derivatives being chosen such that the difference in redox potential ΔE between the redox potential Ei of the aminoindoles, determined at pH 7 in a phosphate medium on a vitreous carbon electrode by voltametry, and the redox potential Eq of the quinone derivative, determined at pH 7 in a phosphate medium by polarography on a mercury electrode relative to the saturated calomel electrode, in such that