10275-21-5 Usage
Description
N,N-diMethyl-2-phenylethylaMine hydrochloride (USAF EL-79), also known as N,N-Dimethylphenethylamine hydrochloride, is a phenethylamine compound that serves as an analytical reference standard. It is primarily used in research and forensic applications due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
N,N-diMethyl-2-phenylethylaMine hydrochloride (USAF EL-79) is used as a synthetic intermediate for the development of squalene synthase inhibitors. These inhibitors play a crucial role in the pharmaceutical industry, as they can potentially be used in the treatment of various diseases, including cancer, by targeting the biosynthesis of cholesterol and other essential biomolecules.
Used in Research and Forensic Applications:
As an analytical reference standard, N,N-diMethyl-2-phenylethylaMine hydrochloride (USAF EL-79) is utilized in research laboratories and forensic settings to analyze and identify the presence of phenethylamine compounds. This aids in the study of their chemical properties, potential applications, and their role in various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 10275-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10275-21:
(7*1)+(6*0)+(5*2)+(4*7)+(3*5)+(2*2)+(1*1)=65
65 % 10 = 5
So 10275-21-5 is a valid CAS Registry Number.
10275-21-5Relevant articles and documents
Synthesis of: N -methylated amines from acyl azides using methanol
Chakrabarti, Kaushik,Dutta, Kuheli,Kundu, Sabuj
, p. 5891 - 5896 (2020/08/21)
The transformation of acyl azide derivatives into N-methylamines was developed using methanol as the C1 source via the one-pot Curtius rearrangement and borrowing hydrogen methodology. Following this protocol, various functionalised N-methylated amines were synthesized using the (NNN)Ru(ii) complex from carboxylic acids via an acyl azide intermediate. Several kinetic studies and DFT calculations were carried out to support the mechanism and also to determine the role of the Ru(ii) complex and base in this transformation.