102755-12-4Relevant articles and documents
Desymmetrization of Symmetrical Triarylcarbinols: Synthesis of 7-Arylfluorenes and a C 2 -Symmetric Chiral BIFOL Phosphoric Acid
Someshwar, Nagamalla,Karthick, Muthupandi,Ramanathan, Chinnasamy Ramaraj
, p. 2253 - 2261 (2017/10/06)
A simple and an efficient method for the synthesis of 7-arylfluorenes by intramolecular cyclization of the corresponding triarylcarbinols in the presence of the solid-acid catalyst NaHSO 4 /SiO 2 has been developed. By using this method, a new chiral diol with a C 2 -symmetric bisfluorenyl unit, 7,7′-diphenyl-7 H,7′ H -5,5′-bibenzo[ c ]fluorene-6,6′-diol (BIFOL), having central chirality was synthesized in an optically active form from (S)-(-)-BINOL-3,3′-dicarboxylic acid. The absolute configuration of the chiral bisfluorene derivative BIFOL was ascertained by single-crystal X-ray analysis. Furthermore, a new chiral phosphoric acid was synthesized from BIFOL and evaluated for enantioselective transfer hydrogenation.
