1027757-13-6

Basic information

• Product Name: 2-BENZYLOXYPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 2-BENZYLOXYPHENYLBORONIC ACID, PINACOL ESTER;2-(2-BENZYLOXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;AKOS BRN-1151;2-(2-Benzyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Benzyloxyphenylboronic acid pinacol ester
• CAS NO: 1027757-13-6
• Molecular Formula: C₁₉H₂₃BO₃
• Molecular Weight: 310.2
• Product Categories: Heterocyclic Compounds
• Mol File: 1027757-13-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 100-104 °C(lit.)
• Boiling Point: 435.2±28.0 °C(Predicted)
• Appearance: /
• Density: 1.08±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BENZYLOXYPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLOXYPHENYLBORONIC ACID, PINACOL ESTER(1027757-13-6)
• EPA Substance Registry System: 2-BENZYLOXYPHENYLBORONIC ACID, PINACOL ESTER(1027757-13-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1027757-13-6(Hazardous Substances Data)

Usage

Uses

2-Benzyloxyphenylboronic acid, pinacol ester

Upstream product

• 20012-63-9 o-(benzyloxy)aniline 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1190387-34-8 C₂₅H₂₄O₅ 
• 1417417-98-1 (4-(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(phenyl)iodonium tosylate 
• 1610518-87-0 7-(2-(benzyloxy)phenyl)-5-methyl-2-((4-(methylsulphonyl)piperazin-1-yl)methyl)thieno[3,2-c]pyridin-4(5H)-one 

Relevant articles and documents

Nickel-Catalyzed Borylation of Aryl- and Benzyltrimethylammonium Salts via C-N Bond Cleavage

By developing a mild Ni-catalyzed system, a method for direct borylation of sp2 and sp3 C-N bonds has been established. The key to this hightly efficient C-N bond borylative cleavage depends on the appropriate choice of the nickel catalyst Ni(COD)2, ICy·HCl as a ligand, and the use of 2-ethoxyethanol as the cosolvent. This transformation shows good functional group compatibility and can serve as a powerful synthetic tool for gram-scale synthesis and late-stage C-N borylation of complex compounds.