102878-19-3

Basic information

• Product Name: Quinoline, 2,4-dichloro-7-methyl-
• CAS NO: 102878-19-3
• Molecular Formula: C10H7Cl2N
• Molecular Weight: 212.078
• Mol File: 102878-19-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Quinoline, 2,4-dichloro-7-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2,4-dichloro-7-methyl-(102878-19-3)
• EPA Substance Registry System: Quinoline, 2,4-dichloro-7-methyl-(102878-19-3)

Safety Data

• Hazardous Substances Data: 102878-19-3(Hazardous Substances Data)

Upstream product

• 98946-74-8 2-amino-3-bromo-7-methyl-quinolin-4-ol 
• 50689-52-6 3-bromo-7-methyl-quinoline-2,4-diol 
• 103037-94-1 2-amino-7-methyl-quinolin-4-ol 
• 141-82-2 malonic acid 
• 108-44-1 1-amino-3-methylbenzene 
• 1677-43-6 7-methyl-quinoline-2,4-diol 

Downstream Products

• 58960-03-5 7-methyl-1,2,3,4-tetrahydroquinoline 
• 109470-07-7 1-benzoyl-7-methyl-1,2,3,4-tetrahydro-quinoline 
• 1424371-17-4 dimethyl 4-(4-(2-chloro-7-methylquinolin-4-yloxy)phenyl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylate 
• 1424371-07-2 diethyl 4-(4-(2-chloro-7-methylquinolin-4-yloxy)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1386328-60-4 ethyl 4-(3-(2-chloro-7-methylquinolin-4-yloxy)phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 

Relevant articles and documents

Regioselective synthesis of 2-chloroquinoline based ethyl 4-(3-hydroxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylates and their In-Silico evaluation against P. Falciparum lactate dehydrogenase

The reaction of various substituted 2, 4-dichloroquinolines with ethyl 4-(3-hydroxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate was carried out in the presence of K2CO3 as a mild and efficient base at controlled temperature leading to novel 2-chloroquinoline based polyhydroquinoline with high regioselectivity. All the synthesized compounds were characterized using IR, NMR, Mass spectral data and then subjected to an in-silico analysis against P. falciparum lactate dehydrogenase.

Ultrasound-promoted synthesis of novel 2-chloroquinolin-4-pyrimidine carboxylate derivatives as potential antibacterial agents

Ultrasound-promoted reaction of substituted 2,4-dichloroquinolines (1) with ethyl 4-(3-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5- carboxylate (2) in the presence of K2CO3 as mild base at moderate temperatures leads

A convenient synthesis of 8,9,10,11-tetrahydrodibenzo[b,h] [1,6]naphthyridin-6(5H)ones

Substituted 8,9,10,11-tetrahydrodibenzo[b,h][1,6]naphthyridin-6(5H)ones (5) have been synthesized by the condensation of 4-amino-3-formylquinolin-2(1H)ones (4) with cyclohexanone in presence of acetic acid and sulphuric acid. The precusors have been obtained by the animation of 4-chloro-3-formylquinolin-2(1H)ones (3).