1029017-11-5Relevant articles and documents
Synthesis of 1-substituted 3-pyridinylmethylidenylindolin-2-ones and 1-substituted 3-quinolinylmethylidenylindolin-2-ones as the enhancers of ATRA-induced differentiation in HL-60 cells
Hung, Chi-Ying,Hsu, Mei-Hua,Huang, Li-Jiau,Hwang, Chrong-Shiong,Lee, On,Wu, Chen-Yi,Chen, Chih-Hung,Kuo, Sheng-Chu
, p. 4222 - 4232 (2008/12/20)
As part of our continuing search for potential differentiation agents, 1-benzyl-3-(4-pyridinylmethylidenyl)indolin-2-one (14) was selected as lead compound, and its new pyridinyl and quinolinyl analogs were synthesized and evaluated for differentiation-in