1029080-53-2

Basic information

• Product Name: 2,2-dichloro-3-(cyclohexyl)cyclobutanone
• Synonyms: 2,2-dichloro-3-(cyclohexyl)cyclobutanone
• CAS NO: 1029080-53-2
• Molecular Weight: 221.127
• Mol File: 1029080-53-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,2-dichloro-3-(cyclohexyl)cyclobutanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dichloro-3-(cyclohexyl)cyclobutanone(1029080-53-2)
• EPA Substance Registry System: 2,2-dichloro-3-(cyclohexyl)cyclobutanone(1029080-53-2)

Safety Data

• Hazardous Substances Data: 1029080-53-2(Hazardous Substances Data)

Upstream product

• 931-48-6 2-cyclohexylacetylene 
• 76-02-8 trifluoroacetyl chloride 
• 695-12-5 vinylcyclohexane 

Downstream Products

• 1029080-67-8 3-cyclohexylcyclobutan-1-one 

Relevant articles and documents

Synthesis of Silylated Cyclobutanone and Cyclobutene Derivatives Involving 1,4-Addition of Zinc-Based Silicon Nucleophiles

A copper-catalyzed conjugate silylation of various cyclobutenone derivatives with Me2PhSiZnCl ? 2LiCl or (Me2PhSi)2Zn ? xLiCl (x≤4) to generate β-silylated cyclobutanones is reported. Trapping the intermediate enolate with ClP(O)(OPh)2 affords silylated enol phosphates that can be further engaged in Kumada cross-coupling reactions to yield silylated cyclobutene derivatives.

Enantioselective baeyer-villiger oxidation catalyzed by palladium(II) complexes with chiral P,N-ligands

(Chemical Equation Presented) Asymmetric Baeyer-Villiger reaction of symmetrical cyclobutanones 1a-j with urea-hydrogen peroxide (UHP) can be catalyzed by a complex of Pd(II) and the new terpene-derived P,N-ligand 7. The resulting lactones 2a-j were obtained in high yields and with good enantioselectivity (≤81% ee).