102916-46-1 Usage
General Description
(S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid (R)-alpha-methylbenzenemethanamine salt is a chemical compound composed of two substances: (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid and (R)-alpha-methylbenzenemethanamine salt. The former is a derivative of pyrrolidine, a five-membered ring compound with heteroatoms, and is commonly used as a chiral building block in the synthesis of pharmaceuticals. The latter is a salt of (R)-alpha-methylbenzenemethanamine, a compound known for its potential as a therapeutic agent in the treatment of central nervous system disorders. (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid (R)-alpha-methylbenzenemethanamine salt may have various applications in the pharmaceutical industry, particularly in the development of new drugs and medications for neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 102916-46-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,9,1 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 102916-46:
(8*1)+(7*0)+(6*2)+(5*9)+(4*1)+(3*6)+(2*4)+(1*6)=101
101 % 10 = 1
So 102916-46-1 is a valid CAS Registry Number.
102916-46-1Relevant articles and documents
Preparation method of levetiracetam and intermediates thereof
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Paragraph 0043; 0048-0051, (2020/01/08)
The invention provides a preparation method of levetiracetam and intermediates thereof. The specific steps are as follows: dropwise adding pyrrolidone into a toluene solution of sodium methoxide or sodium hydride, performing concentrating to dryness after a reaction is completed, adding toluene again, dropwise adding ethyl 2-bromobutyrate, and carrying out a reaction by heating to obtain a compound of a formula 3; adding a NaOH aqueous solution to the compound of the formula 3, performing heating until a reaction is completed, and dropwise adding concentrated hydrochloric acid to precipitate acompound of a formula 4; carrying out a reaction of the compound of the formula 4, R-(+)-phenylethylamine, and triethylamine to obtain a compound of a formula 6; performing hydrolysis by a NaOH solution, acidification by concentrated hydrochloric acid, and purification to a compound of a formula 7; and performing esterification by TsOH/EtOH to obtain a compound of a formula 8, and then performingammonia hydrolysis to obtain levetiracetam.
