1029272-92-1

Basic information

• Product Name: 1-methyl-3-phenylindolizine
• Synonyms: 1-methyl-3-phenylindolizine
• CAS NO: 1029272-92-1
• Molecular Weight: 207.275
• Mol File: 1029272-92-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-phenylindolizine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-phenylindolizine(1029272-92-1)
• EPA Substance Registry System: 1-methyl-3-phenylindolizine(1029272-92-1)

Safety Data

• Hazardous Substances Data: 1029272-92-1(Hazardous Substances Data)

Upstream product

• 1122-62-9 2-acetylpyridine 
• 536-74-3 phenylacetylene 
• 55690-09-0 (E)-4-phenyl-2-(pyrid-2-yl)-3-buten-2-yl 
• 943901-55-1 1-phenyl-3-(pyridin-2-yl)prop-2-yn-1-ol 
• 54856-82-5 3-methyl-[1,2,3]triazolo[1,5-a]pyridine 
• 917-54-4 methyllithium 

Relevant articles and documents

Cobalt(II)-based Metalloradical Activation of 2-(Diazomethyl)pyridines for Radical Transannulation and Cyclopropanation

A new catalytic method for the denitrogenative transannulation/cyclopropanation of in-situ-generated 2-(diazomethyl)pyridines is described using a cobalt-catalyzed radical-activation mechanism. The method takes advantage of the inherent properties of a CoIII-carbene radical intermediate and is the first report of denitrogenative transannulation/cyclopropanation by a radical-activation mechanism, which is supported by various control experiments. The synthetic benefits of the metalloradical approach are showcased with a short total synthesis of (±)-monomorine.

Cu-catalyzed transannulation reaction of pyridotriazoles with terminal alkynes under aerobic conditions: Efficient synthesis of indolizines

A Cu(i)-catalyzed denitrogenative transannulation reaction of pyridotriazoles with terminal alkynes en route to indolizines was developed. Compared to the previously reported Rh-catalyzed transannulation reaction, this Cu-catalyzed method features aerobic conditions and a much broader scope of pyridotriazoles and alkynes.

Low temperature organocopper-mediated two-component cross coupling/cycloisomerization approach toward N-fused heterocycles

(Chemical Equation Presented) Organocopper reagents smoothly react with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this novel cascade transformation, which proceeds via an SN2′ substitution followed by a subsequent cycloisomerization step.