1029273-04-8Relevant articles and documents
Organocopper-mediated two-component SN2’-substitution cascade towards N-fused heterocycles
Chernyak,Gevorgyan
, p. 1516 - 1526 (2018/01/26)
Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a “double duty” in this cascade transformation, which proceeds through an SN2’-substitution followed by a consequent cycloisomerization step.