1029604-58-7

Basic information

• Product Name: (R,E)-ethyl 2-(benzyl((trimethylsilyl)methyl)amino)-4-phenylbut-3-enoate
• Synonyms: (R,E)-ethyl 2-(benzyl((trimethylsilyl)methyl)amino)-4-phenylbut-3-enoate
• CAS NO: 1029604-58-7
• Molecular Weight: 381.59
• Mol File: 1029604-58-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,E)-ethyl 2-(benzyl((trimethylsilyl)methyl)amino)-4-phenylbut-3-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-ethyl 2-(benzyl((trimethylsilyl)methyl)amino)-4-phenylbut-3-enoate(1029604-58-7)
• EPA Substance Registry System: (R,E)-ethyl 2-(benzyl((trimethylsilyl)methyl)amino)-4-phenylbut-3-enoate(1029604-58-7)

Safety Data

• Hazardous Substances Data: 1029604-58-7(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 1029603-94-8 (E)-diethyl styrylboronate 
• 53215-95-5 N-(trimethylsilylmethyl)benzylamine 

Relevant articles and documents

Asymmetric petasis reactions catalyzed by chiral biphenols

Chiral biphenols catalyze the enantioselective Petasis reaction of alkenyl boronates, secondary amines, and ethyl glyoxylate. The reaction requires the use of 15 mol % of (S)-VAPOL as the catalyst, alkenyl boronates as nucleophiles, ethyl glyoxylate as the aldehyde component, and 3 A molecular sieves as an additive. The chiral α-amino ester products are obtained in good yields (71-92%) and high enantiomeric ratios (89:11-98:2). Mechanistic investigations indicate single ligand exchange of acyclic boronate with VAPOL and tetracoordinate boronate intermediates. Copyright