1029720-67-9

Basic information

• Product Name: 5-broMo-3-chloroisoquinoline
• Synonyms: 5-broMo-3-chloroisoquinoline
• CAS NO: 1029720-67-9
• Molecular Formula: C₉H₅BrClN
• Molecular Weight: 242.4997
• EINECS: -0
• Mol File: 1029720-67-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 349.5±22.0 °C(Predicted)
• Appearance: /
• Density: 1.673±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 0.86±0.43(Predicted)
• CAS DataBase Reference: 5-broMo-3-chloroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-3-chloroisoquinoline(1029720-67-9)
• EPA Substance Registry System: 5-broMo-3-chloroisoquinoline(1029720-67-9)

Safety Data

• Hazardous Substances Data: 1029720-67-9(Hazardous Substances Data)

Usage

General Description

5-bromo-3-chloroisoquinoline is a chemical compound that belongs to the class of heterocyclic compounds and is specifically an isoquinoline derivative. It is a synthetic chemical that has a molecular formula of C9H5BrClN and a molecular weight of 233.5 g/mol. 5-broMo-3-chloroisoquinoline contains a bromine atom and a chlorine atom attached to a 3-position isoquinoline ring, which imparts unique chemical and physical properties to the compound. It is used in the field of organic chemistry as a building block for the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, its unique structure and reactivity make it a valuable tool for studying chemical reactions and mechanisms.

Upstream product

• 1215767-89-7 5-bromo-1,3-dichloroisoquinoline 
• 7742-73-6 1,3-dichloroisoquinoline 
• 58142-49-7 3-chloro-5-amino-isoquinoline 

Downstream Products

• 1254715-58-6 C₁₄H₁₄ClNO₂ 
• 1578243-82-9 N-(4-methoxyphenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 
• 1578243-74-9 (3-methoxy-4-((5-(pyridin-3-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-54-5 (4-((5-(1-(2-(dimethylamino)ethyl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)-3-methoxyphenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-86-3 N-(2,4-dimethoxyphenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 
• 1578243-84-1 N-(2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 
• 1578243-81-8 5-(furan-2-yl)-N-(4-methoxyphenyl)isoquinolin-3-amine 
• 1578243-75-0 (3-chloro-4-((5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-73-8 (3-methoxy-4-((5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-72-7 (3-methoxy-4-((5-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-56-7 tert-butyl 4-(4-(3-((2-methoxy-4-(3-methoxyazetidine-1-carbonyl)phenyl)amino)isoquinolin-5-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate 

Relevant articles and documents

METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS

The subject matter described herein is directed to ferroportin inhibitor compounds of Formula (I) and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.