10300-27-3 Usage
Description
2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one, also known as Guanosine with the hydrogen on the hydroxyl at position C-3' substituted with a methyl group, is a chemical compound derived from guanosine. It features a unique structure with a methyl group substitution at the C-3' position, which may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one is used as a potential therapeutic agent for various diseases due to its unique chemical structure and properties. The compound may be further investigated for its potential in targeting specific biological pathways or as a building block for the development of new drugs.
Used in Research and Development:
In the field of research and development, 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one can be used as a starting material or a reference compound for the synthesis of novel molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Chemical Synthesis:
2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one can be utilized as an intermediate or a building block in the synthesis of more complex molecules, such as nucleoside analogs, which have applications in antiviral, anticancer, and immunosuppressive therapies. Its unique structure may also be exploited to develop new chemical reactions or synthetic methods.
Please note that the provided materials do not specify any direct applications for the compound. The uses listed above are hypothetical and based on the general properties and potential of compounds with similar structures. Further research and development would be required to validate these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 10300-27-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,0 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10300-27:
(7*1)+(6*0)+(5*3)+(4*0)+(3*0)+(2*2)+(1*7)=33
33 % 10 = 3
So 10300-27-3 is a valid CAS Registry Number.
10300-27-3Relevant articles and documents
Synthesis of 9-(3-Deoxy-3-fluoro-&β-D-ribofuranosyl)guanine, a New Potent Antiviral Agent
Puech, Frederic,Gosselin, Gilles,Imbach, Jean-Louis
, p. 955 - 957 (2007/10/02)
The title compound (5) was prepared by reacting a corresponding nucleoside of xylo configuration with (diethylamino)sulphur trifluoride (DAST).
Methylation study of ribonucleosides, deoxyribonucleosides, and 2′-O-methylribonucleosides with trimethylsulphonium hydroxide and trimethylsulphonium iodide. Influence of the 2′-hydroxy-groups on the reactivity of the base moieties of ribonucleosides
Yamauchi, Kiyoshi,Nakagima, Toru,Kinoshita, Masayoshi
, p. 2787 - 2792 (2007/10/02)
Methylations of the naturally occuring ribonucleoside (1), deoxyribonucleoside (2), and 2′-O-methylribonucleoside (3) were carried out using trimethylsulphonium hydroxide (Me3SOH) and trimethylsulphonium iodide (Me3Sl). The base moiety of (2) and (3) are more reactive than the corresponding base moiety of (1). The sites and extent of methylation of (2) are considerably different from those of (1), but are almost identical with those of (3). The reactivities of (1)-(3) are discussed in connection to an intramolecular interaction of the 2′-OH groups with the base moiety of (1). The methylating characteristics of Me 3SOH and Me3Sl are also described. The kinetics indicate an SN2 mechanism for methylation of nucleosides by Me 3S+ ions.
